TESTOSTERONE PELLETS: Do They Work?

testosterone pellets

Not much is written about testosterone pellets, so we decided to super-focus an article dedicated to the subject and find out whether this type of therapy works. Testosterone pellet therapy is a treatment where small pellets are inserted just below the skin.

The pellets themselves are made up from estradiol or testosterone, along with a very small dose of stearic acid. The combination of these hormones is compressed into tiny solid cylinders.

If you had to compare a testosterone pellet with something more familiar in terms of size, a comparison with a grain of rice would be a good one.

Recent medical data suggested that hormone replacement therapy which involves pellet implants is one of the most effective methods to deliver hormones in both men and women.

Testosterone pellet implants work by consistently releasing small doses of hormones, which are ideal if you are looking for optimum results. Typically, men need to undergo this therapy for a period of between four and six months.

This method is designed to avoid any fluctuations of hormonal levels which are common in other types of testosterone replacement therapies. It must be noted, that testosterone pellets will not increase the risk of developing blood clots, which is commonly the case with most synthetic hormone replacement therapies.

It has been suggested that testosterone pellets have been effective in treating migraine and menstrual headaches.

In women, testosterone pellets have worked to combat the vaginal dryness, as well as incontinence.

Testosterone is very important for both men and women because it helps to relieve symptoms of depression, help to increase energy, increase sense of well-being, as well as improving memory and concentration capacity.

When testosterone is delivered via a testosterone pellet, it has shown to increase muscle strength, as well as the bone density, whilst working to decrease body fat.

Both men and women need the “adequate levels” of this hormone to allow them to enjoy the “optimal” mental and physical health as well as preventing chronic illnesses such as Parkinson’s disease and Alzheimer’s, both of which are sometimes linked to low testosterone levels.

Testosterone pellets proven effective, even for people that have tried other types of hormonal therapies which failed to work. According to some medical professionals, testosterone pellets are the safest method of hormone delivery available out there.

How Are Testosterone Pellets Inserted into the Body?

Testosterone pellets are inserted seamlessly and without pain because the procedure is normally carried out under local anesthesia. It is normal for the testosterone pellets to be inserted into the upper area of the buttocks via a tiny incision.

The whole experience is entirely dependent on the experience of the health care professional that is performing the procedure.

Can Testosterone Pellets Cause Side-Effects?

Testosterone pellets are not entirely side-effect free. Some complications can arise as a result of inserting the pellets which include minor bruising, bleeding, skin infections, and discoloration of the skin.

However, the side-effects are slightly harsher when it involves women. The extra testosterone released from testosterone pellets can cause the growth of facial hair. A much safer and an equally effective method of increasing testosterone is by using a testosterone boosting supplement.

Testosterone boosting supplements come with less side-effects and are less intrusive.

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Why Do Testosterone Pellets Have a Low Profile?

The reason for the low profile of testosterone pellets is that they are not patented, nor are they marketed in the United States. They are more commonly used across Europe and Australia where dedicated pharmaceutical companies produce them.

However, testosterone pellets were very common in the United States in the 1940s, all the way through to the 1970s.

Why Do Men Need Hormone Replacement Therapy?

As you may well know, testosterone production begins to drop in men at certain stages of life. Very few men are able to maintain the right levels of testosterone past their 30s and 40s. It is advisable for men to be tested for signs of testosterone deficiency.

Testosterone deficiency introduces many problems for men, including fatigue and depression, erectile dysfunction, declining bone density, as well as developing sleep problems.

What If My Doctor Advises against Using Testosterone Pellets?

It is very common for medical practitioners to dismiss this method of testosterone therapy. The emphasis lies on the patient who needs to make an informed decision.

Once the testosterone pellets are inserted, it is normal for the individuals concerned to start experiencing more energy, sleeping better at night and generally feeling happier .Furthermore, bone density as well as the muscle mass will increase, and the excess body fat will soon start to diminish.

Patients will notice an instant increase in energy levels, coordination will drastically improve and any type of physical performance will be enhanced. Skin-tone as well as the hair texture will see improvements.

The ability to concentrate and retain things in the memory will also benefit from an increase in testosterone levels, not to mention the astonishing boost in the libido.

Please note that the above-mentioned benefits will result from an increase in testosterone, and not necessarily just from using testosterone pellets.

It is important to make an informed decision on which method you would like to pursue to help you increase your testosterone levels safely.

How Long Do Testosterone Pellets Take to Work?

It all depends on the individual. Some patients begin to notice the benefits of testosterone pellets within the first 24 hours. The speed of effectiveness is dependent on the individual’s diet and lifestyle.

How Long Do Testosterone Pellets Last?

Usually, testosterone pellets last between 4 to 6 months. Once the testosterone pellets are inserted into the buttock area, they do not need to be removed. Once they have finished releasing testosterone, they dissolve into the body.

What to Do after Having Testosterone Pellets Inserted…

What to Do after Having Testosterone Pellets Inserted…As you can see, testosterone pellets may not be entirely suitable for everybody.

Many people, including myself, are afraid of incisions and the site of blood, which are common with intrusive hormonal replacement therapies.

A much less intrusive method (as stated earlier) is by using a natural testosterone booster. Natural testosterone boosters are less invasive and can be equally as effective in increasing testosterone levels as testosterone pellets.

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Have you ever used testosterone pellets? If so, we would love to hear about your experience. Please leave your comments in the box below.

22 Comments

  1. Dawn

    November 11, 2015 at 1:58 am

    Please help me!!!!! I am a 44 year old female…please continue to read even if this is a male site. I can’t find anywhere else to get help.
    My testosterone level was 29 when my Dr. advised me to have the pellet inserted. It was 302 after one month. it’s been a month since that test and I haven’t been re-tested.
    I’m MISERABLE!!!!!! I have severe pelvic floor pain since the pellet was inserted. This pain is comparable to restless leg except it’s restless anus, vagina and clitoris!!!! Add a microwaved porcupine into each orifice and you have my pain!
    What are my options to gain relief? I can’t sleep, sit, stand, think, and am easily agitated from these side effects. I’m seriously getting on my own nerves from never getting relief.
    Please advise me with something besides telling me to consult with my Physician who seems to be clueless.
    I’m begging for help!!!
    Thank You,
    Dawn

  2. Robert Moore

    December 22, 2015 at 2:55 am

    54 yo. First time. 83 is my level and 606 is the minimum normal for my age. Still new to the experience but pain in buttox has been difficult. Still painful after 5 days.

  3. Ginger

    January 3, 2016 at 7:56 pm

    Dear Dawn,

    I am the same age and I have just finished my first pellet and having a second inserted tomorrow afternoon.
    I have not experienced the pain you are describing (perhaps your body is having an allergic reaction) unfortunately all that can be done is to let it dissolve which takes about 3 months, so maybe it is almost out of your system by now.
    I did, however, experience the severe agitation and irritation and very bad PMS symptoms/cramps–wanted to get away from myself. My doctor put me on DIM 13C 50/50 to decrease the “bad” estrogen that the testosterone can actually begin to make more of in your body. He also increased the progesterone that I take at night. The hormones helped me and calmed me within 2 days.
    I hope this info is somewhat helpful. Hormones are so delicate and difficult to deal with.
    Best Wishes and feel better!

  4. JW

    April 16, 2016 at 12:55 am

    I am going through pure HELL with Testosterone pellets. 45- female. Doc knew weight gain was almost going to stop me from getting them but assured me they would help me to be able to loose weight and build lean muscle. In 2 weeks I gained 8 lbs and I was a size zero. I went up 2 sizes and have been barking at everyone! I then had bloodwork 5 weeks in to find out it almost all converted to Estrogen with a level of 825!!!!!!!!!!!!!!!!!!!!!!! It was 74 before. Noone will take them out. I had to get put on an estrogen blocker (like Tamoxifen)the drug indicated Only post breast cancer. It has ruined my self esteem and these doctors should NOTTTTTTTTTTTTTT be doing these. I should have been warned this all could have happened but rather I was told the opposite with no fair balance of what COULD happen! Please someone help me. How long until my face and hips and stomache look normal again. I exercise 7 days a week

  5. Sheryl

    April 27, 2016 at 6:28 pm

    I’m a 49 yr old woman on my 3rd round of pellet injection. I can understand and relate to much said above so maybe I can help others. First of all, and most important, your doctor needs to be educated on what they are doing. Mine has been through a urologist I had <2.5 testosterone level when I went to him for chronic UTIs. He started me on a low dose pellet reject me a month later for how I was feeling and my levels before he put a booster in to add more. It sounds from stories above that doctors just went too high with the first pellet. I am 5'4 and 2 years post menopause had gained about 15 pounds after menopause and weighed about 1:28. One of my complaints was the belly I developed after menopause. After the first ballot I did gain weight but my urologist told me to expect water weight gain and they gave me a diuretic to counteract that it worked well. I don't see anyone above speaking of the expected water weight and what your doctor did to prevent or get rid of it. So yes you will gain weight if your doctor doesn't do something about it but it is water weight obviously my urologist knew what he was doing by being proactive with a diuretic.

    After the first ballot I started noticing my belly going-away increased energy and definitely increased libido. I had a whole lot more sensitive sensation in the female clitoral area. After the second palette there was less water weight gain and I continued to lose weight.

    I have now lost every pound gained after menopause. I no longer get water weight after the injections. However, the pellets are painful for 2 to 3 days after insertion. My mom will be sore to put pressure on or when squatting which goes away within a few days of the procedure.

    Again, from Reading above it sounds as if doctors don't know what they are doing those levels are too high for a woman. An ideal level would normally be between 50 to 70 but that can vary from Woman to Woman. A number of 300 is extremely excessive you're likely to start getting manly attributes such as more facial hair, deepening voice, enlarged clitoris, etc.
    I wouldn't let these negative experiences prevent you from obtaining the benefits of these pellets. But instead hopefully you'll know to ensure your doctor of choice knows what they are doing and is very educated and experienced at doing this. Again, mine was with my urologist and he started me at a very low dose and then 30 days later added what they call a booster after he saw how the first insertion went. And again, told me about the water weight gain so we could be proactive. I read nothing of those two in the above stories

  6. Sheryl

    April 27, 2016 at 6:31 pm

    I’m a 49 yr old woman on my 3rd round of pellet injection. I can understand and relate to much said above so maybe I can help others. First of all, and most important, your doctor needs to be educated on what they are doing. Mine has been through a urologist I had <2.5 testosterone level when I went to him for chronic UTIs. He started me on a low dose pellet retested me a month later for how I was feeling and my levels before he put a booster in to add more. It sounds from stories above that doctors just went too high with the first pellet. I am 5'4 and 2 years post menopause had gained about 15 pounds after menopause and weighed about 128. One of my complaints was the belly I developed after menopause. After the first pellet I did gain weight but my urologist told me to expect water weight gain and they gave me a diuretic to counteract it worked well. I don't see anyone above speaking of the expected water weight and what your doctor did to prevent or get rid of it. So yes you will gain weight if your doctor doesn't do something about it but it is water weight. Obviously my urologist knew what he was doing by being proactive with a diuretic.

    After the first pellet I started noticing my belly going away increased energy and definitely increased libido. I had a whole lot more sensitive sensation in the female clitoral area. After the second pellet there was less water weight gain and I continued to loose weight.

    I have now lost every pound gained after menopause. I no longer get water weight after the injections. However, the pellets are painful for 2 to 3 days after insertion. My bum will be sore to put pressure on or when squatting which goes away within a few days of the procedure.

    Again, from Reading above it sounds as if doctors don't know what they are doing those levels are too high for a woman. An ideal level would normally be between 50 to 70 but that can vary from Woman to Woman. A number of 300 is extremely excessive you're likely to start getting manly attributes such as more facial hair, deepening voice, enlarged clitoris, etc.
    I wouldn't let these negative experiences prevent you from obtaining the benefits of these pellets. But instead hopefully you'll know to ensure your doctor of choice knows what they are doing and is very educated and experienced at doing this. Again, mine was with my urologist and he started me at a very low dose and then 30 days later added what they call a booster after he saw how the first insertion went. And again, told me about the water weight gain so we could be proactive. I read nothing of those two in the above stories

  7. Brian

    June 17, 2016 at 1:02 pm

    Hello,

    I am a 58 year old male and over the last two-three years my level has dropped to a level of 4, yes a 4. That 4 was brought up to a 74 with a myriad of topicals over the same period. I literally have tried every topical out there and they all had peaks and valleys and eventually quit working all together. I was only able to get my levels to around 200 with topicals and then hit a plateau.

    I then was told to go to testosterone injections every 2 weeks for about 6 months. I was able to get as high as a 1200 level one time and feeling awesome but to retain that level I had to have injections every single week. Unfortunately with injections I developed an abscess every 3rd or 4th injection and I had to be put on a regimen of antibiotics and I missed injections for 2-3 weeks and lost all I has gained. So after 2 years of no libido, no energy, terrible fatigue or inability to focus I decided to go to the pellets per my physicians insistence.

    This week I had a 9 pellet insertion this past Tuesday. I am still in an immense amount of pain and soreness even today now being Friday. I plan to call the doctor today to see if I have developed an infection. Upon pellet insertion the doctor did mention that I might need to be put on antibiotics especially coupled with my history of getting an abscess with every 3rd or 4th testosterone injection. To date, I do not feel that there has been any change in my well being but I have made the decision to go back to injections as to not to have to deal with the pain of this pellet procedure. The pain is like nothing I have experienced previously even with the abscesses.

    Still Praying for a Miracle!

  8. John

    August 12, 2016 at 2:07 am

    78 years old. The pellet implants have changed my life since age 71. I drive semi truck, high climb/top 150 ft. trees, etc. I went for an extended time recently without the implants. (My bad) My recent test was 29, which is low. I have a great deal more strength, better moods, endurance, energy and other things. The injections did not work well, as my T level would drop rapidly, after an injection. The pellets are much more stable with my T level. I believe all men over 40 should have the T level test. I now know men in their 20s who need testerone therapy. Don’t stay tired, have your T level tested. I originally saw a brochure in my urologist’s office. I asked about it & he gave me the T blood test. Take charge and ASK YOUR DOCTOR FOR THE T TEST!!!!!!

  9. Taylor

    October 12, 2016 at 4:54 am

    I’m a 21 y/o Male, I’ve had low t since i was 15. My lowest total t was 163 and right now im at 211, the testosterone of an 80 year old man. Not fun at all being that I am only 21… I was just given 8 200mg pellets to start off with and a 250mg im shot for the next 2 weeks to help get me to normal levels and an estrogen blocker. Its been 8 hours since the procedure and the pain is very minimum thus far, but I have high hopes… My old endo got my levels to 300 amd said as long as I have enough energy to get out of bed I’m doing fine. Also the same endo wouldn’t treat my hypothyroidism… I found out that going to a privat clinic that deals in low t and thyroid is the best bet for getting the help you need, at least for me anyway. But I have learned that the endos in Az are not that great.

  10. Caroline

    November 21, 2016 at 5:42 pm

    I’m going in tomorrow for the implant and a bit scared…
    I am a 34 female and my testosterone level is 1.10 that is critically low.
    My question is – how painful is it after the procedure and how long does the pain last for?
    I have to work the next day for long hours and it involves standing, picking up things and carrying as well as traveling.
    My doctor (gynecologist) never mentioned the pain. His secretary said “yes” when I asked her if I can still go to gym afterwards…
    Please help!

  11. Dr Spring

    November 21, 2016 at 10:12 pm

    Hello Caroline, unfortunately different people have different pain thresholds and its difficult in trying to predict exactly how you will feel after the procedure. I would ask your Doctor directly.

  12. Taylor

    November 22, 2016 at 3:01 pm

    I can tell you that you will feel it for a couple weeks, I’ve had mine for a month and Now I got sore in that spot when I walk not sure if it hit a nerve of what. But the first few days to week suck.

  13. Caroline

    November 23, 2016 at 6:46 pm

    I went yesterday and was petrified! The doctor gave me a local anesthetic and when that large needle went in, I felt nothing as the area was numb. The entire prosedure took about 10 – 15 min, including the local anesthetic.
    After that I was able to walk and go to work. He told me I should wait at least two days before I go to the gym. I was given one pellet of 50mg.
    I got painkillers just incase. Also its best not to shower for 24h afterwards, so I had my shower before my appointment. I was at work all day today and had no pain. I haven’t taken any painkillers at all. It was slightly itchy, but I think it means that it’s busy healing. I still have my plaster on at the moment. He told me that if an infection occurs I should come see him and another small risk is that it can come out, other than that, I should start to feel some effects after two weeks.
    After six weeks I will have another blood test done for testosterone and estrogen to see where I am at. It lasts 3-6 months, but every 6 weeks is a good indication where your levels are at.
    So still no pain and all good for now.
    I’m wondering if your doctor hit a nerve Taylor.
    I went to a obstetrician gynecologist to have mine done.

  14. Caroline

    November 23, 2016 at 7:03 pm

    Oh goodness, I just looked at my results and I made a mistake, my level is now at 0.10 not 1.10, that’s like nothing! So I will keep you all posted on what is happening on my side

  15. Jeannie Beck

    January 28, 2017 at 7:17 pm

    My 87 year old dad who had a triple bypass, a quadruple bypass, and was on blood thinners for hereditary blood clots was given Testosterone Pellets in June 2016 and December 2016 in Sarasota, Florida. It hurt his memory very bad and caused small STROKES. He complained about his but hurting BADLY in DEC. 2016 and thats how we found out he did it. He was always fine and in pretty good health especially his memory BEFORE THE PELLETS AND NOW he had to be PLACED in an ASSISTED LIVING CENTER. He can’t even remember who CHARGED medicare and laid him on a table for the INJECTIONS. My family is DEVASTATED! He is on Paxil now for Anxiety and Depression and he wasn’t like this before the PELLET IMPLANTS. I am so upset! I’m ready to go to WASHINGTON! I’m writing to the Florida States Attorney RIGHT NOW. My dad almost died! He keeps asking us to take the PELLETS OUT so we are investigating Removal.

  16. Esther

    February 4, 2017 at 7:09 am

    I had a testosterone implant last week but not feeling the effects as yet. It is my 2nd implant. The 1st went well as no issues upon insertion and I felt more energetic, my hair shone, boobs got bigger and libido was amazing – I am nearly 60. However, this time, blood started squirting out – the doc hit an artery! Stitched up and felt wobbly for a couple of days but it’s healing well and I took stitches out today. Just waiting for the energy and libido boost to come soon – fingers crossed!

  17. Rebekah Miller

    February 26, 2017 at 4:44 am

    My husband and I received the pellets about a month ago. I have not seen any benefits of this hormone therapy. In fact, as weird as it may seem, I feel like I am more tired. I have gained weight because of increased appetite. I don’t want to work out or do anything. I figured this would help increase energy and I would want to go work out, but it has done the oppposite. Now my husband on the other hand, has had wonderful benefits. He has more energy and has been working out everyday. He is staying up later because he has more energy throughout the day and is not as tired. I don’t know why it worked for him and not me, but it is extremely frustrating!

  18. Norma Aceval

    April 19, 2017 at 3:53 am

    Plz help me I’m 64 yrs old female had the pellet inserted 3-7-17 along with 100mg and 50 mg pills I sleep all day gained 8 pounds and got very bad blisters all over my head and itch very much The so called person told me to stop taking the 100 mg pill and take the 50mg pill st night. Nothing h had changed I was not given ant information on side affects or what to expect. I’ stopped taking all pills and am still getting blisters full of puss on head. Plz help me as I can not get anyone to call me back either. I am miserable

  19. Michelle

    May 25, 2017 at 9:29 pm

    Michelle

    I am a 65 year old woman and am on my 3rd round of pellets. I highly recommend them. My energy level is great, my moods are great and my relationship with my husband is definitely benefitting. Although 65, I am responding like I am 40. Plus, 15 lbs just melted off. The injection of the pellets is the only discomfort I get and it is only for a few days. If you keep the ice pack on you won’t even be bothered.

  20. Christine

    June 7, 2017 at 5:04 pm

    Same here Rebekah! My levels were almost 0 so my doctor recommended the implant. She said it would help me lose weight, have more energy, and increase libido.Instead I have gained a size, feel irritable and tired, and my migraines which had lessened are back. I really woyld like to have the pellet removed. I can’t imagine feeling this way for 4-6 months!!

  21. Lisa B.

    June 28, 2017 at 9:27 pm

    I’m a 48 year old female with a complete hysterectomy, therefore no hormones. I received my 3rd pellet in May. I’ve had terrific results! I’m not sure about some of the folks here. The testosterone pellet was only just FDA approved for females in the US recently. Even then, only a 75mg pellet has been approved for females. It’s different for males. I can’t imagine the effects of 300mg! God help you!! In Europe they have much more experience using the pellets. There the beginning dosage recommended for females is a 100mg testosterone pellet. I don’t believe that they recommend,anywhere,to go as high as 300mg for a female. In Europe they also say a blood test is the least reliable method of testing levels of hormones. Although it’s a good baseline, it’s more important to note how the person is feeling and how negatively/positively they,themselves feel the pellets are affecting them. The two together are used to decide whether to increase or decrease the dosage. As for the gentleman who suffered a stroke…..I’m not sure who put the pellet into him, but it very clearly says in ALL the literature that testosterone should not be given to anyone at risk for developing blood clots or who is on anticoagulant medications. I’m an RN, and anyone in the medical field should know better than to give an elderly man on anticoagulants testosterone of any kind due to the risk of developing blood clots. I’m so sorry this has happened to him and your family!
    The pellets, if given properly are not painful. They do not carry the same risks as standard Hormone Replacement Therapy. The risk of breast cancer and heart disease for women is next to nothing! It’s more effective than taking hormones by mouth or via a patch or vreams. Your body uses only what it needs as it needs it. The advantages, if done by a physician who really knows what they are doing, far outweigh any risk!!

  22. Vinny

    August 23, 2017 at 1:28 pm

    I’m a 55 year old male, and had 12 pellets inserted 6 days ago. My Testosterone was 380 in 1/17, then 127 on 7/17, 194 a week later. GUYS, TESTOSTERONE LEVELS ARE MEANINGLESS ALONE!! You could be told you’re normal, but still suffer Low T, and vice versa, someone could have a level of 200, and they’re fine. I’ve had erectile problems for years, low libido, etc. Took PDE5 inhibitors early on, and they worked great, but then they started be be ineffective, obviously due to the decrease in T and resultant low libido. PDE5s need a “sex drive” to work. Finally, my wife said you need to do something about this. I had a full “male” physical. Physical exam of my penis, new blood work, Arterial/Doppler to test blood flow and erectile function (normal), Rigiscan (device you wear at night for 3 nights, show some leakage) to measure noctural erections (this measure function, but removes any mental/anxiety stimuli since you are in REM sleep) arterial elasticity, etc. Diagnosis is I have the same issue that most men my age start to suffer, basically being half hard, or losing your erection, or never getting one at the right time… It’s very common guys. Trust me. … It’s due to a couple of things…. Combo of low Libido, which causes you to lose the erection, then the bad mental state you get in from this happening a few times, that then leads to horrible “situational” anxiety when you’re going to have sex, which then causes your body to get into a mode of releasing epinephrine (Fight or Flight, caused by mental anxiety, or as docs call it “psychogenic ED”). The constant release of epinephrine over time due to the anxiety then results in Corporal Venous Occlusion issues(“CVOD”, the inability to hold blood in your erection because the Epi is telling your venous system in your penis to dilate and release the blood, pretty much similar to the natural response you have after you climax) It becomes a serious mental/chemical vicious cycle that just gets worse and worse if you don’t do something about it. GUYS, MANY SUFFER FROM THIS, there is NOTHING to be embarrassed about. Well, guess what Low T does? There are studies that link low T levels to corporal venous occlusion disorder, hence by the PDE5s work when you’re younger and have more free T, but become ineffective when your T drops to a certain level. Goodbye boner.
    Anyway, It’s been 5 days since I got my pellets, insertion site is back to normal… first couple of days, my mental acuity started to improve, on the 4th day, I woke up with a throbbing nighttime erection! It’s been a while since that has happened. Day 5 and 6, nighttime erections are common, my libido has increased around 30% so far, I actually had a sex dream, I can’t remember the last time I had one. Morning wood returning. It’s only been 6 days. Looking forward to week 2 and 3. Go in for a blood test in two weeks to check Estradiol levels, Free T, DHT.

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